The human immune system is finely tuned to detect and destroy viral threats. But this same defense system can misfire. When ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

Aston University bioscientist Dr John Reynolds has won a £125,000 Springboard grant from the Academy of Medical Sciences (AMS) for research into neurodegeneration caused by a rare genetic disease.

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

What causes gray matter loss in Multiple Sclerosis? New research identifies DNA damage in CUX2 neurons as a primary driver of MS progression.

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Researchers have identified a specific class of brain neurons that dies during multiple sclerosis because inflammation ...

A group of nerve cells essential for cognition may be especially vulnerable to DNA damage upon exposure to inflammation in MS.

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

Melatonin intervention linked to borderline significant increase in urinary 8-OH-dG, which is indicator of oxidative DNA damage repair capacity. (HealthDay News) — For night shift workers, melatonin ...

Melatonin supplementation may help offset the DNA damage associated with night shift work by boosting the body's ability to repair it, suggest the findings of a small clinical trial published online ...