FPR2 activation regulates ISC proliferation and differentiation by activating the Wnt, Notch, and Hippo pathways via the PKC-ERK signaling axis. The intestinal epithelium undergoes rapid renewal every ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

On the left, large intestine tissue from a healthy person; on the right, from a patient with active C. difficile infection. The white areas show the cells that line the intestine (epithelial cells).

Out of touch: Understanding the frequency and trajectory of chemotherapy-induced neuropathy peripheral (CIPN) in breast cancer survivors. Incidence of ocular toxicities in patients with ...

A recent study in Nature Microbiology investigated how Salmonella typhimurium targets the gut epithelium and localizes to the follicle-associated epithelium (FAE) of the small intestine. The human gut ...