"Leptin resistance is a major barrier to treating obesity," senior author Işın Çakır said in a Pitt news release via UPMC.

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. Although previous ...

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger ...

Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use. Featured in the February ...

BATON ROUGE – Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use. Featured in the ...

A research group has identified the so-called PNOC/NPY nerve cells in the brains of mice. When activated, these cells increase food intake and lead to obesity. Interestingly, these nerve cells are ...

Palatin Technologies Inc. has obtained U.S. orphan drug designation for PL-7737 for leptin receptor (LEPR) deficiency, including obesity caused by this condition.

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The research, led by ...

CRANBURY, N.J., March 25, 2025 /PRNewswire/ -- Palatin Technologies, Inc. (PTN), a biopharmaceutical company developing first-in-class medicines based on molecules that modulate the activity of the ...

Axons from AgRP neurons, in red, innervate oxytocin neurons, in green, in the PVH. Neuronal activity of AgRP neurons is required for normal targeting of their axons to oxytocin neurons, as well as for ...