Understanding which cells within a tumor will go on to form metastases remains one of the major challenges in cancer research ...

Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood or immune cells. But cancer cells also cross established boundaries, grow ...

This work, published in Nature Communications, opens new avenues for identifying tumors with a high risk of developing ...

Researchers at Ben-Gurion University of the Negev have identified a protein that plays a central role in enabling aggressive breast cancer cells to spread to other parts of the body.

Researchers at Ben-Gurion University of the Negev have identified a protein that plays a central role in enabling aggressive ...

Cell migration is a multistep process essential to various physiological functions, including immune cell movement and embryonic development, as well as pathological conditions like tumor metastasis.

Metastases are a key problem in many types of cancer. As descendants of the primary tumor, they can grow in other organs ...

Building on an in vivo genetic screen in mice to identify host regulators of cancer metastasis, 4 Yang et al. focused on ARHGEF1, which is 1 of 15 genes whose disruption in host tissues decreases the ...

Successful test in breast cancer patients: the active agent digoxin, a cardiac medication, dissolves clusters of circulating breast cancer cells in the blood, thus reducing the risk of metastases ...