With new COVID variant-specific booster shots set to roll out in the coming week, vaccine scientists argue that more research is needed to understand how a person's early immune response -- either ...

Original Antigenic Sin (OAS) is the “tendency of individuals exposed to a given strain of influenza to respond with antibodies that react more strongly to the first strain of influenza they had met in ...

Researchers have learned more about when OAS occurs, which can help scientists improve the effectiveness of vaccines and boosters. The findings have been reported in Nature. "Our goal was to ...

Our immune systems react most strongly to the viral strains we encountered in our childhoods. Scientists call this original antigenic sin (OAS)—the body’s first blush with a virus like influenza or ...

In a recent article published in The Journal of Clinical Investigation, researchers collated the findings of studies relating original antigenic sin (OAS) with severe acute respiratory syndrome ...

I suppose it is appropriate to begin with a confession; I was drawn to the study by the phrase “original antigenic sin.” I stayed for the content, which taught me more about our immune responses.

Our immune systems react most strongly to the viral strains we encountered in our childhoods. Scientists call this original antigenic sin (OAS)—the body's first blush with a virus like influenza or ...