Compared with human-specific transcriptional factors, human-specific lncRNAs identified upon human lncRNAs’ orthologs in mammals have greatly evolved DNA-binding sites in archaic and modern humans in ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Salk Institute researchers find new mode of epigenetic targeting, showing for the first time that genetic sequences can direct new DNA methylation patterns in plants LA JOLLA (November 21, 2025)—All ...

Learn about comparative gene expression studies in Alzheimer's disease and other conditions in Mayo Clinic's Precision Medicine in Neurodegeneration Lab.

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression. Focusing ...

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk," may actually play powerful roles in regulating gene expression. Focusing ...

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...

The authors conclude that mRNA vaccines “induce a gene-altering [mode of action], reprogramming host expression programs” that go far beyond inflammatory responses to Spike protein. Effects include ...